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ABSTRACT

Schwannomatosis, also known as neurofibromatosis type III, is a rare condition characterized by the development of multiple schwannomas along peripheral nerve sheaths. Although open surgery remains the standard treatment, the evolution of minimally invasive techniques has expanded the indications of endoscopic spine surgery, including for benign expansile lesions. We present the case of a 76-year-old female with thoracic pain, lower limb neurological deficits, and imaging findings suggestive of thoracic schwannomas associated with a disc herniation. The patient underwent a posterolateral extraforaminal endoscopic resection of both the disc herniation and the adjacent nerve sheath tumor. The procedure was uneventful, with partial improvement in pain and motor function. Further investigation confirmed the diagnosis of Schwannomatosis with multiple lesions throughout the spinal axis. Endoscopic surgery proved to be a feasible and safe approach for decompression in cases of isolated thoracic schwannomas. Further studies are warranted to confirm its role in the treatment of spinal neoplastic conditions. .

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